CD45.1 Antikörper (violetFluor™ 450)

Produktnummer ABIN2567751

Der Maus Monoklonal Anti-CD45.1-Antikörper wurde für FACS validiert. Er ist geeignet, CD45.1 in Proben von Maus zu detektieren.

Kurzübersicht für CD45.1 Antikörper (violetFluor™ 450) (ABIN2567751)

Target: CD45.1 (CD45 (CD45.1 Allogen))

Reaktivität: Maus

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser CD45.1 Antikörper ist konjugiert mit violetFluor™ 450

Applikation: Flow Cytometry (FACS)

Klon: A20

Produktdetails anti-CD45.1 Antikörper (violetFluor™ 450)

Spezifität: The A20 monoclonal antibody reacts with the leukocytes of the CD45.1-expressing mouse strains (DA, SJL/J, RIII, and STS/A).

Aufreinigung: The monoclonal antibody was purified utilizing affinity chromatography and unreacted dye was removed from the product.

Isotyp: IgG2a kappa

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 0.2 mg/mL

Buffer: Phosphate-buffered aqueous solution, ≤0.09 % Sodium azide, may contain carrier protein/stabilizer, ph7.2.

Lagerung: 4 °C

Informationen zur Lagerung: The product should be stored undiluted at 4°C and should be protected from prolonged exposure to light. Do not freeze.

Details zu CD45.1

Target: CD45.1 (CD45 (CD45.1 Allogen))

Andere Bezeichnung: CD45.1

Hintergrund: The A20 monoclonal antibody reacts with the leukocytes of the CD45.1-expressing mouse strains (DA, SJL/J, RIII, and STS/A). It does not cross-react with cells that express CD45.2. The CD45 Molecule is a member of the Protein Tyrosine Phosphatase (PTP) family, because its intracellular region contains two PTP domains. The extracellular region's variability is caused by different levels of glycosylation, and the splicing of the 4, 5, and 6 exons. The isoforms found in the mouse strains depend on the activation state, maturation stage and cell type, and are very important in B and T lymphocytes antigen receptor signal transduction. The A20 antibody inhibits some of the B lymphocytes responses, from CD45.1-expressing mice, to lipopolysaccharides and antigens. BG Violet 450 conjugate is an alternative to the Pacific Blue, eFluor 450, or BD Horizon V450 dyes. It is excited by the violet (405 nm) laser, with a peak emission of 450nm.

Gen-ID: 19264

UniProt: P06800